September 1, 2014

New Alzheimer’s Drugs Continue to Fail Where Coconut Oil Shines

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Brian Shilhavy
Health Impact News

The Failure of Big Pharma in Treating Alzheimer’s Disease

Two more Alzheimer’s drug trials have failed. Melissa Healy of the LA Times reported on the most recent failures of Big Pharma to develop Alzheimer’s drugs in January 2014:

Two biological therapies designed to improve the clearance of sticky plaques from the brains of those with Alzheimer’s disease have failed to slow the steady loss of cognitive function in patients with mild to moderate forms of the degenerative disorder.

In late clinical-trial findings published Wednesday in the New England Journal of Medicine, the monoclonal antibodies known as solanezumab and bapineuzumab were shown ineffective at changing the downward cognitive trajectory of Alzheimer’s patients. (Full Story here.)

These are the most recent failures, and they follow a long list of drug failures in Big Pharma’s attempt to develop pharmaceutical products to treat Alzheimer’s Disease. Drug companies Pfizer and Medivation abandoned their Alzheimer’s drug dimebon in January 2012, because the drug not only did not help patients in trials, but it made patients worse. The expensive drug had already reached phase III trials.

Seniors diagnosed with Alzheimer’s Disease represent a huge market for pharmaceutical companies, as Alzheimer’s Disease is increasing rapidly, affecting many millions of seniors. Pharmaceutical companies are anxious to tap into this market, and several pharmaceutical companies are currently trying to develop an Alzheimer’s vaccine. (See efforts to develop Alzheimer’s vaccine in Sweden, Canada, and the U.S.)

In the history of drug marketing, the single most successful drug to ever hit the market was a drug targeted at seniors: Lipitor, the statin drug designed to lower cholesterol levels.

Lipitor has since had its patent expire, allowing cheaper statin generics to come into the market. But during its strongest years in sales, Lipitor almost outsold all other pharmaceutical drugs combined, making it the most profitable drug in history.

Today, about one out of every four Americans over the age of 55 is taking a statin drug. So this age group is a very lucrative market for the pharmaceutical companies, who would desperately like to have a successful Alzheimer’s drug or vaccine be approved for sale.

Are Pharmaceutical Drugs One of the Causes of Alzheimer’s Disease?

In 2011, Dr. Stephanie Seneff published research looking at the effects of a low-fat diet and statin drugs in relation to Alzheimer’s Disease. This research noticed a strong correlation between insulin resistance in the brain and early Alzheimer’s Disease, suggesting that Alzheimer’s might be considered a neuroendocrine disorder of the brain or so-called “type 3 diabetes”.

But the study’s main conclusions regarding the early causes of Alzheimer’s Disease centered around the transport of cholesterol from the blood stream to the brain. The research stated that there is mounting evidence which suggests that a defect in cholesterol metabolism in the brain may play an important role in Alzheimer’s Disease. A nice summary of the brain’s dependency on cholesterol is given:

The brain represents only 2% of the body’s total mass, but contains 25% of the total cholesterol. Cholesterol is required everywhere in the brain as an antioxidant, an electrical insulator (in order to prevent ion leakage), as a structural scaffold for the neural network, and a functional component of all membranes. Cholesterol is also utilized in the wrapping and synaptic delivery of the neurotransmitters. It also plays an important role in the formation and functioning of synapses in the brain. (Study here.)

They point to several studies that show that there is a lack of cholesterol in the brains of Alzheimer’s patients which is so vital for several functions, and also note that other studies show this cholesterol deficiency in dementia and Parkinson’s disease as well. In contrast, high cholesterol levels are positively correlated with longevity in people over 85 years old, and in some cases has been shown to be associated with better memory function and reduced dementia.

In 2012, another study looked at the effects of statin cholesterol-lowering drugs on Alzheimer’s patients. The patients in the study had their statin medication stopped for six weeks, and then restarted. The results showed that during the six weeks when their statins were stopped, the basic brain function of the individuals improved. When the drugs were restarted, brain function got worse again. (Study here.)

So if statin cholesterol-lowering drugs are part of the problem in causing Alzheimer’s Disease, can we really expect that pharmaceutical companies will be able to develop drugs to cure Alzheimer’s?

Coconut Oil is More Successful than Drugs in Treating Alzheimer’s Disease

I realize that to make a statement that coconut oil is more successful than drugs in treating Alzheimer’s Disease is not much of a statement at all, if drugs are one of the primary problems. Quitting pharmaceutical drugs altogether and doing nothing else is probably better than taking drugs to treat Alzheimer’s.

The anecdotal evidence of the success in stopping, and even reversing, Alzheimer’s in some people using coconut oil, however, is so remarkable, that it is foolish to discount what this simple dietary oil can do. After all, it is a fact that Alzheimer’s drugs have been a huge failure until now.

There is currently one trial ongoing looking at the effects of coconut oil on Alzheimer’s Disease. It was started in 2013 at the University of South Florida’s Health Byrd Alzheimer’s Institute. They have a study currently in progress where they have enrolled 65 individuals with mild to moderate Alzheimer’s to measure the effects of coconut oil, versus a placebo, on the disease. The funding reportedly came from a private foundation, as there is obviously no interest or government funds available to research coconut oil, since it would not bring any profit to pharmaceutical companies with their billions of dollars in revenue and government tax-payer funded research dollars at stake. Read more about the study here.

People all across America, and around the world, are not waiting for the results of research trials however. Many people with Alzheimer’s Disease are already seeing a huge improvement, and in some cases a full reversal, of the disease after starting with coconut oil. Here is a partial list of testimonials that we have published here at Health Impact News:

Why Does Coconut Oil Work in Treating Alzheimer’s?

The first thing we should make clear is that not everyone who tries coconut oil with dementia or Alzheimer’s sees the same results as reported in these testimonials. Coconut oil does seem to be more effective in those who do not have advanced stages of Alzheimer’s and are still in the earlier stages, although we have seen a few testimonials for late-stage Alzheimer’s as well (See: Woman with End-stage Alzheimer’s Sees Improvement in One Week after Starting Coconut Oil)

However, if we look at Alzheimer’s Disease as a “type 3″ diabetes and an insulin resistance problem, coconut oil makes a lot of sense, as does a ketogenic high-fat diet. Coconut oil is known as a rich source of ketone energy, supplying an alternate form of energy to the brain. In fact, pharmaceutical companies are currently trying to develop drugs that mimic the same “ketonic” effect that can be achieved via a high-fat diet. (See: Study: Coconut Oil Could Prevent Neurodegeneration in Diseases like Alzheimer’s)

To learn more about the ketogenic diet, insulin resistance, coconut oil, and treating Alzheimer’s disease, watch this very informative round table discussion with 5 medical doctors, science author Gary Taubes, and nutritionist Robb Wolf:

Also, if the brain is being starved of cholesterol, coconut oil might provide benefits by increasing HDL cholesterol levels. A study appearing in the American Journal of Cardiology in February 2011 showed that the higher men’s HDL cholesterol levels, the longer they lived and the more likely it was that they would reach the age of 85. (Study abstract.)

The high-fat low-carb ketogenic diet has been around since the 1920s, when it was developed at John Hopkins. But it fell out of favor with doctors after the USDA dietary guidelines started condemning saturated fats and cholesterol.

However, the research linking saturated fats and cholesterol to heart disease has never been based on solid data. Recent research has completely exonerated saturated fat from being associated with heart disease. A 2010 meta-study published in the American Journal of Clinical Nutrition looked at almost 350,000 people over a 23 year period and found no association between saturated fat and heart disease. (Study abstract.) A similar meta-study was conducted and published in May of 2013, analyzing the existing medical literature regarding dietary fats and heart disease in the journal Advances in Nutrition. (See: Study: Saturated Fat Not Associated with Risk of Coronary Artery Disease, Coconut Oil and Dairy Fat Healthy)

So if we remove our bias against cholesterol and saturated fat, we begin to see why the ketogenic diet has been so effective for so many neurological disorders over the years. It was originally developed as a dietary cure for children with epilepsy, and worked when drugs did not. (See: Ketogenic Diet Can be used to Control Seizures) Dr. Eugene Arnold of the Ohio State University Medical Center has also studied how a lack of cholesterol can be a contributing factor to autism. (See Adding Cholesterol to Diet Reduces Autism Symptoms)

Dietary Guidelines for Using Coconut Oil in Alzheimer’s Prevention and Cure

One of the criticisms against coconut oil for Alzheimer’s treatment is that it is not well-tolerated by many people. The primary reason this criticism is made, we believe, is because people read these testimonials of how coconut oil has worked so effectively and immediately begin consuming large amounts of coconut oil. In many of the stories that have been reported, seniors are consuming a tremendous amount of coconut oil. Some people are consuming 3 tablespoons three times a day, for a total of 9 tablespoons a day.

For almost all people, this will cause a lot of problems, such as diarrhea. Most people do not tolerate large amounts of coconut oil or other fats right away. One must start out slow with the amount of coconut oil they can tolerate, and then gradually increase the amount to see the desired effect. Also, it is best to start out consuming coconut oil with other foods that are high in protein and fiber, as this is how it is packaged in nature within the coconut meat. Many people mix it in with oatmeal, for example. While oatmeal is not a desirable food allowed in a strict ketogenic diet limiting carbohydrates, the importance of acclimating the body to coconut oil should be seen as more important in the beginning, before moving on to a more strict ketogenic diet.

Nine tablespoons a day is the upper limit of what we have seen people report for therapeutic amounts for Alzheimer’s or other neurological diseases such as ALS. Many others report therapeutic amounts at 3 tablespoons a day, although even that amount is probably too much for most people to start. Much smaller amounts, such a teaspoon at a time mixed with other foods, is best to start and then work slowly towards higher amounts.

As to the type of coconut oil to consume, virgin coconut oil is best, as it is the least processed. Organic is not as important, as very few coconut trees in tropical climates have pesticides applied to them. However, even refined coconut oil has the same medium chain fatty acids that are responsible for the ketogenic effect. So if a cheaper refined coconut oil is all you can afford, don’t be afraid to buy it thinking it is something “bad” simply because it is refined. As long as it is not hydrogenated, it is still a healthy oil. We are not aware of any hydrogenated edible coconut oils sold in the U.S. market, but there may be some in tropical countries where they want to keep the coconut oil solid in higher temperatures.  Virgin coconut oils, particularly traditionally produced virgin coconut oils, have higher amounts of antioxidants and possibly other nutrients, so they are preferable if you can afford them.

The one “coconut oil” that is best to avoid is “liquid coconut oil” or what is sometimes referred to as “MCT Oil.” This is not a true coconut oil, but a manufactured product where coconut oil is fractionated, and lauric acid is removed. Lauric acid is the most dominant, and most important, component of coconut oil, and the only other natural abundant source is human breast milk. Lauric acid is a valuable ingredient that is often removed from coconut oil, and the remaining oil left over is what is marketed as “liquid coconut oil” or “MCT Oil.” For more information on this see: Is Liquid Coconut Oil that stays Liquid in Your Refrigerator Real Coconut Oil?

Conclusion: Diet and Prevention is the Best Strategy to Avoid or Reverse Alzheimer’s Disease

There is strong evidence that one of the main contributing factors for Alzheimer’s Disease is a diet too low in fats and excessive pharmaceutical drugs. The low-fat dietary advice, and the demonization of cholesterol, has led to poor health and the development of worthless and harmful statin drugs. The data and evidence on the health benefits of coconut oil and the ketogenic diet is overwhelming today, not only for Alzheimer’s Disease, but for a whole host of other diseases as well.

Research more about the Ketogenic Diet here. For more research on coconut oil and Alzheimer’s Disease, visit the CoconutOil.com’s Alzheimer’s research page. You can also read many research studies on cholesterol and saturated fat at CoconutOil.com.

For other research on dietary intervention for Alzheimer’s Disease, here are some more articles to consider:

DHA From Omega 3 Fats

Turmeric Produces ‘Remarkable’ Recovery in Alzheimer’s Patients

Could Eating This Simple Black Seed Prevent Alzheimer’s Disease?

Ubiquinol Rescues Cells from Statin-Induced Side Effects

Studies Show Cinnamon and B Vitamins can Help Prevent Alzheimer’s

Study: Vitamin B May Protect Against Alzheimer’s

Saffron: Ancient Healing Powers Confirmed by Science

Diet and Toxins Cause Alzheimer’s, Not Genetics

New Research Continues to Show Alzheimer’s is a Type 3 Diabetes

Research: Foods/Spices Slow, Perhaps Reverse Alzheimer’s

Vitamin D and Cholesterol Needed to Prevent Alzheimer’s – Coconut Oil Provides Needed Fuel for the Brain

 

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About the authors: Unlike many people who write about coconut oil by simply reading about it, Brian and Marianita Shilhavy actually lived in a coconut producing area of the Philippines for several years. Marianita Jader Shilhavy grew up on a coconut plantation in the Philippines and in a culture that consumed significant amounts of coconut fat in their diet. She later went on to earn her degree in nutrition and worked as a nutritionist in the Philippines. Brian Shilhavy also lived in the Philippines for several years with Marianita and their 3 children observing firsthand the differences between the diet and health of the younger generation and those of Marianita’s parents’ generation still consuming a traditional diet. This led to years of studying Philippine nutrition and dietary patterns first hand while living in a rural farming community in the Philippines. They are authors of the best-selling book: Virgin Coconut Oil: How it has changed people’s lives and how it can change yours!

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Asian Farmers and Scientists Say No to GMO Golden Rice

Asian Farmers and Scientists Say No to GMO Golden Rice

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GM Golden Rice was developed at the International Rice Research Institute (IRRI) in the Philippines with the hope that it could provide more vitamin A through beta carotene. The project was a huge disaster, however, and basically shelved for years. But then Bill Gates came along, the college-drop-out-turned-billionaire who started Microsoft Corp., looking for something to spend his billions of dollars to promote. All of a sudden, with big money providing jobs to pursue a failed project, GM Golden Rice has new life.

There are multiple problems with GMO Golden Rice, including the fact that the people from rice-producing countries do not want it!

Recently many top scientists and farmer advocates from rice-producing countries met in the Philippines in an effort to try and stop more field testing, and the commercialization of Golden Rice. The science behind Golden Rice does not prove benefits, and it threatens genetic diversity among traditional rice varieties which is necessary in many parts of the world that experience natural and man-made disasters. Like any GMO seed crop, Golden Rice would take the future of farming in rice-producing countries away from the control of the farmers and give it to multinational corporations that would then control the rice seed supplies.

MASIPAG (Farmer-Scientist Partnership for Development) in the Philippines hosted the event earlier this year, and has recently provided video interviews from some of the participants in English.

Study: Virgin Coconut Oil Reduces Symptoms of Chemo – Improves Quality of Life for Breast Cancer Patients

Study: Virgin Coconut Oil Reduces Symptoms of Chemo – Improves Quality of Life for Breast Cancer Patients

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Once again, research into the health benefits of coconut oil is mainly being done outside of the U.S., primarily in coconut-producing countries. Here in the U.S., only pharmaceutical drugs can make health claims, by law. The FDA regulates all health claims, and only allows pharmaceutical companies that have gone through the lengthy and costly drug approval process to make such claims. No company in the U.S. would spend that kind of money on research for a product found in nature that cannot be patented.

A study just published in the journal Lipids in Health and Disease looked at Malaysian women suffering from breast cancer. The study discovered that stage 3 and 4 breast cancer women who supplemented their diet with virgin coconut oil during breast cancer treatment improved fatigue, dyspnea, sleep difficulties, and loss of appetite compared to the control group. Virgin coconut oil consumption during chemotherapy also helped improve the functional status and global Quality Of Life of these breast cancer patients. In addition, it reduced the symptoms related to side effects of chemotherapy.

Using Coconut Oil in Cold Drinks

Using Coconut Oil in Cold Drinks

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Cold drinks are a popular summer staple that coffeehouses and restaurants make a killing off of every year with their ridiculous prices. However, there is little need to buy them. Making most of these drinks at home is easy, not to mention with far more healthy potential when you control what goes into them.

Adding coconut oil to your blended cold drinks is one way to get your daily dose of coconut oil without it being bothersome or boring. Not only that, but the addition of coconut oil will also give your endurance and energy a boost, keeping you going throughout the day or acting as a quick pick me up along with some natural fruit as the day drags on.

CDC Whistleblower: Mercury in Vaccines Given to Pregnant Women Linked to Autism

CDC Whistleblower: Mercury in Vaccines Given to Pregnant Women Linked to Autism

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Today, the Autism Media Channel released a short video where CDC whistle-blower Dr. William Thompson states, in a phone call to Dr. Brian Hooker, that injecting mercury into pregnant women creates a “clear and present danger” to the unborn child. Thimerosal, a form of mercury used as a preservative in vaccines, was removed from most childhood vaccines a few years ago, but is still in the annual flu shot, which is recommended for pregnant women.

Dr. Thompson, in the video below, insists that this mercury in vaccines causes “tics” in children, and these tics are 4 times more prevalent in kids with autism. “Tics” are defined on the CDC website as: “Tics are sudden twitches, movements, or sounds that people do repeatedly. People who have tics cannot stop their body from doing these things. For example, a person with a motor tic might keep blinking over and over again. Or, a person with a vocal tic might make a grunting sound unwillingly.”

Watch the short 1 minute video.

CDC Responds: Admits Omitting Vaccine Data Linking Vaccines to Higher Rates of Autism

CDC Responds: Admits Omitting Vaccine Data Linking Vaccines to Higher Rates of Autism

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While the mainstream media continues to ignore what is becoming the biggest news event of the year, the CDC is scrambling to respond to damaging data that they were forced to release earlier this year clearly showing they had data linking vaccines to autism that they hid from the public. This issue can longer be hidden since one of the top researchers within the CDC, who co-authored several of the studies that supposedly showed no link between vaccines and autism, has decided to become a whistle-blower. He has yet to make an official statement, and it is thought that his attorney is seeking official whistle-blower status before he does so.

The CDC, on the other hand, has responded to Dr. Brian Hooker’s newly published study reanalyzing a 2004 CDC study that excluded data showing a significant increase in autism among African American boys who were vaccinated with the MMR vaccine. They supplied a response to the Next News Network, admitting they excluded certain data, and the reasons for doing so. Next News interviewed Dr. Hooker to discuss the CDC response. Dr. Hooker, through a 10-year legal battle with the CDC and hundreds of Freedom of Information requests, finally received the entire data sets from the CDC after Congressman Bill Posey stepped in to put pressure on them to release it. We also now know that Dr. Hooker was in contact for more than a year with an insider in the CDC who has become a whistle-blower, which undoubtedly applied pressure on the CDC to obey the law and release the data.

In this interview, Dr. Hooker states that the CDC is lying in their response, and the reason they are doing so is to protect the reputation of the MMR vaccine. He also points out that the CDC purchases $4 billion of vaccines from the vaccine industry every year, and are the last ones who should be trusted to do studies on vaccine safety due to their huge conflict of interest.

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