October 2, 2014

Research: Foods/Spices Slow, Perhaps Reverse Alzheimer’s

Pin It

by Sayer Ji
GreenMedInfo.com

Did you know that so-called “incurable” neurodegenerative conditions such as Alzheimer’s disease can be slowed, if not also partially reversed? Regeneration, after all, is the default state of the human body.

This may sound all the more surprising when you consider that over 1,000 clinical trials have been performed, and billions of dollars expended, in order find an effective solution, without any significant progress in reversing the underlying trajectory of the condition.[i]

In fact, some of the very same patented chemicals approved by the FDA to “treat” the symptoms of Alzheimer’s disease, e.g. donepizl (trade name Aricept), are chemically related to insecticides, chemical weapons and venom, and are notorious for greatly increasing the risk of seizures in those to whom they are prescribed.

Back in 2006, a study published in the Journal of Alzheimer’s Disease (AD) found that a class of compounds found within turmeric known as curcuminoids enhance the amyloid-beta uptake of macrophages within Alzheimer’s disease patients.  Amyloid-beta (Abeta) plaque is found in unnaturally elevated levels in neurodegenerative disorders such as AD, and is believed to contribute to the underlying disease process.[ii]

In the study, researchers treated the macrophages of six AD patients and 3 controls by curcuminoids and measured the Abeta uptake.  The results were as follows:

After treatment of macrophages with curcuminoids, Abeta uptake by macrophages of three of the six AD patients was significantly (P<0.001 to 0.081) increased.

They concluded:

Immunomodulation of the innate immune system by curcuminoids might be a safe approach to immune clearance of amyloidosis in AD brain.

Another study published in the same journal in 2009 found that vitamin D3 increased the efficacy of curcuminoids in enhancing the clearance of the amyloid-beta plaque.

While these two studies are amazing, they are not novel. In fact, we have identified 30 studies in total which show the potential value of curcuminoids in Alzheimer’s disease prevention and treatment.  These study abstracts can be viewed in full on our Alzheimer’s disease page.

Curcumin is, in fact, only one of several natural compounds and/or therapeutic modalities with promising anti-Alzheimer’s activity. Others include:

Coconut Oil (MCTs): Alzheimer’s disease is associated with a pathological decrease in brain glucose, the brain’s principal source of energy.  In 2006, a study was published in the journal of  Neurobiology of Aging, involving subjects with mild cognitive impairment who were given an oral dose of medium chain triglycerides. When tested 90 minutes later, subjects showed increased cognitive performance, believed to be associated with increased ketone bodies and their brain-metabolism enhancing effects.[iii]

Alpha-Lipoic Acid: A 2007 study published in the Journal  of Neural Transmission found alpha-lipoic acid “dramatically lowers” disease progression in Alzheimer’s disease patients who received 600 mg a day for 12 months.[iv]

B-Complex: A 2011 study published in the International Journal of Geriatric Psychiatry found B-complex to slow cognitive and clinical decline in people with mild cognitive impairment.  The researchers noted that homocysteine is a risk factor for AD and that B vitamins may slow brain atrophy by suppressing homocysteine accumulation. [v]

Alpha-GPC: A 2003 study published in the journal Clinical Therapeutics found that the cholinergic precursors choline and lecithin (phosphatidylcholine) in the form of choline alfoscerate (Alpha-GPC), and naturally found in neuronal membranes, was tolerable and effective in the treatment of the cognitive symptoms of dementia disorders of the Alzheimer type.[vi]

Gingko Biloba: In 2006 the European Journal of Neurology published the results of a 24-week randomized, placebo-controlled, double-blind study showing an extract of this plant was as effective as Aricept (donepezil) for mild-to-moderate Alzheimer’s disease.[vii]Another study published in 2009 found that it was as effective as Aricept in improving symptoms of Alzheimer’s disease, but with less side effects.[viii]

Saffron: A 2009 study published in the journal Psychopharmacology found that 22-weeks of saffron supplementation compared favorably to Aricept in the treatment of mild-to-moderate Alzheimer’s disease.[ix]

The Mediterranean diet – The Mediterranean diet is one of the most extensively research therapeutic diets known in the scientific literature.  There are over 50 diseases that have been studied to be mitigated or prevented through employing the Mediterranean Diet. A 2011 study published in the journal Expert Review of Neurotherapeutics found that adherence to a Mediterranean-type diet could be associated with slower cognitive decline, reduced risk of progression from mild cognitive impairment to Alzheimer’s disease (AD), reduced risk of AD and a decreased all-cause mortality in AD patients.[x]  Another 2007 study found lower mortality in Alzheimer’s disease patients consuming a Mediterranean diet.[xi]

Vitamin E – A 2009 study published in 2009 in the journal Dementia and Geriatric Cognitive Disorders found that vitamin E use is associated with improved survival in an Alzheimer’s disease cohort.[xii]


[i]  ClinicalTrials.gov, Alzheimer Studies: 1,088

[ii]  Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer’s disease patients. J Alzheimers Dis. 2006 Sep;10(1):1-7.

[iii] Effects of beta-hydroxybutyrate on cognition in memory-impaired adults. J Agric Food Chem. 2006 Mar 22;54(6):2123-8.

[iv] Alpha-lipoic acid as a new treatment option for Alzheimer’s disease–a 48 months follow-up analysis. J Neural Transm Suppl. 2007;(72):189-93.

[vi] Cognitive improvement in mild to moderate Alzheimer’s dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial. Clin Ther. 2003 Jan;25(1):178-93.

[vii] Ginkgo biloba and donepezil: a comparison in the treatment of Alzheimer’s dementia in a randomized placebo-controlled double-blind study. Eur J Neurol. 2006 Sep;13(9):981-5.

[viii] Ginkgo biloba extract EGb 761(R), donepezil or both combined in the treatment of Alzheimer’s disease with neuropsychiatric features: a randomised, double-blind, exploratory trial. Aging Ment Health. 2009 Mar;13(2):183-90.

[x] Diet and Alzheimer’s disease risk factors or prevention: the current evidence. Expert Rev Neurother. 2011 May ;11(5):677-708.

[xi] Mediterranean diet and Alzheimer disease mortality. Neurology. 2007 Sep 11 ;69(11):1084-93. PMID: 17846408

[xii] Vitamin E use is associated with improved survival in an Alzheimer’s disease cohort. Dement Geriatr Cogn Disord. 2009;28(6):536-40. Epub 2009 Dec 10.

Read the full article and comment here: http://www.greenmedinfo.com/blog/research-foodsspices-slow-perhaps-reverse-alzheimers

 

pin it button Research: Foods/Spices Slow, Perhaps Reverse Alzheimers

Virgin Coconut Oil Beats Drugs in Treating Alzheimer’s

A Holistic Guide to Geriatric Care – eBook

Virgin Coconut Oil Beats Drugs in Treating Alzheimers ebook cover Research: Foods/Spices Slow, Perhaps Reverse Alzheimers

In this book we look at the problems and causes of Alzheimer’s as they are related to an epidemic of prescription drugs being marketed to seniors, and we look at the strong evidence for dietary intervention, starting with coconut oil.

We bring you the stories of 10 different families who saw Alzheimer’s lessened or reversed by adding coconut oil to their diet, which is representative of thousands of others who are experiencing similar results. We offer guidelines on usage and types of coconut oil to consider, as well as other non-drug tips for holistic geriatric care.

Our target audience is the millions of caregivers out there loving caring for our senior population who will find it difficult to get this information from their doctors or medical professionals not trained in these areas.

Read Virgin Coconut Oil Beats Drugs in Treating Alzheimer’s on your mobile device!

$1.99

appstore icon Research: Foods/Spices Slow, Perhaps Reverse Alzheimers

googleplay app store Research: Foods/Spices Slow, Perhaps Reverse Alzheimers

kindle logo sm Research: Foods/Spices Slow, Perhaps Reverse Alzheimers

nook logo Research: Foods/Spices Slow, Perhaps Reverse Alzheimers

 

0 commentsback to post

Other articlesgo to homepage

Chili Pepper’s Remarkable Role in Pain Relief and Reducing Tumors

Chili Pepper’s Remarkable Role in Pain Relief and Reducing Tumors

Pin It

Capsaicin, found in chili peppers, helps alleviate pain in part by depleting your body’s supply of substance P, a chemical component of nerve cells that transmits pain signals to your brain. It also works by de-sensitizing sensory receptors in your skin.

Capsaicin has been shown to activate cell receptors in your intestinal lining, creating a reaction that lowers the risk of tumors. Capsaicin has both antioxidant and anti-inflammatory properties and has even shown some promise for cancer treatment.

FDA Targets Essentials Oils: Sees EOs as Threat to New Ebola Drugs?

FDA Targets Essentials Oils: Sees EOs as Threat to New Ebola Drugs?

Pin It

The FDA issued warning letters this week to the two largest distributors of essentials oils in the United Sates, Young Living and dōTERRA. The FDA is claiming that their products are being marketed as unapproved drugs. The companies have to remove all health claims and take corrective actions, or face very serious legal action, which can include armed federal marshals coming to their warehouses and seizing all of their inventory.

This is of course not the first time that the FDA has gone after companies selling natural products, products that could never be patented, for making health claims about those products. They have a history of issuing warning letters against the producers and marketers of such things as walnuts, cranberries, elderberry juice, coconut oil, and many more. The FDA requires that companies selling natural products and making health claims get their permission first, by going through a lengthy and costly drug approval process.

These two companies have been around for many years, and the independent distributors have been making health claims for the essential oils for a very long time. So why is the FDA acting now?

Study: Oil Pulling and Gum Massage Inhibits Gingivitis and Dental Plaque

Study: Oil Pulling and Gum Massage Inhibits Gingivitis and Dental Plaque

Pin It

While conventional dentistry is pouring chemicals into our mouths, ancient Ayurveda has been preventing gingivitis and periodontal disease with natural oils for thousands of years.

Ayurveda has been recommending oil pulling and gum massage for thousands of years to help prevent gum disease and plaque build up. Yet the chemical industry is convinced their antibacterial mouthwashes and rinses are the answer. The heck with ‘superstitious’ ancient therapies – they say.

However, modern research is now proving the oldest continuous medicine was not wrong about oil pulling or gum massage.

Feds Say Cannabis Is Not Medicine While Holding The Patent on Cannabis as Medicine

Feds Say Cannabis Is Not Medicine While Holding The Patent on Cannabis as Medicine

Pin It

Ben Swann travels to Colorado to learn the truth about cannabis as medicine and what government isn’t telling you.

Are GMO Foods, Vaccines, and Big Pharma Producing an Infertile Generation?

Are GMO Foods, Vaccines, and Big Pharma Producing an Infertile Generation?

Pin It

The U.S. fertility rates are at all-time record lows. Are we watching the leading edge of a slowly moving tidal wave of infertility? I wasn’t sure what is really happening with human fertility until I took a hard look at the data and the science. I now believe that there is strong reason to be concerned about the emerging trend of infertility. What is causing the current generation of child-bearing aged adults to become infertile?

read more


Get the news right in your inbox!