Sign of the times? US stocks up on Amgen’s radiation sickness drug Nplate

by Fraiser Kansteiner
Fierce Pharma

In what could be a troubling sign of the times, the United States is stocking up on radiation sickness drugs.

Wednesday, the U.S. Department of Health and Human Services (HHS) said it’s throwing down $290 million to lock up an undisclosed amount of Amgen’s blood disorder med Nplate, which is approved to treat blood cell injuries linked to acute radiation syndrome (ARS) in kids and adults.

ARS, also known as radiation sickness, occurs when a person’s body is exposed to a high dose of penetrating radiation, which is capable of “reaching internal organs in a matter of seconds,” HHS explained in a release. ARS injuries can lead to symptoms such as impaired blood clotting from low platelet counts, which can trigger uncontrolled and potentially “life-threatening” bleeds.

The Amgen drug is otherwise approved for kids and adults with the blood disorder immune thrombocytopenia, which causes patients to suffer from low platelet counts.

HHS did not clarify its rationale behind the Nplate stock-up, though the move comes amid escalating tensions between Russia and Ukraine. Russian President Vladimir Putin has recently invoked the threat of nuclear retaliation, painting the conflict as an existential feud between Russia and the West.

Experts are divided on whether Putin is bluffing, though Reuters reports the White House is taking the threats seriously. Meanwhile, neighboring countries to Ukraine such as Poland have reportedly been distributing iodine tablets in response to shelling around Zaporizhzhia nuclear power plant in Ukraine, for which Russia and Ukraine blame each other.

Big West Coast Biotech Amgen developed Nplate in conjunction with the U.S. Biomedical Advanced Research and Development Authority (BARDA), more recently known for its extensive deals with vaccine players at the height of the COVID-19 pandemic. The blood disorder med was also created with the help of the National Institute of Allergy and Infectious Diseases.

For the new deal, BARDA is leveraging its power under 2004’s Project Bioshield act, as well as furnishing the $290 million in Project Bioshield funding to purchase the undisclosed Nplate supply.

Read the full article at Fierce Pharma.

Nuclear warhead arsenal lacks security

by Harry the Greek

Does the Pentagon have any idea where they have stashed their nuclear weapons arsenal?

Have they ever maintained a chain of custody to verify their inventory of nuclear weapons is safe and secure?

The answer is, “No.”

According to the Government Accountability Office (GAO).

The GAO is known as “the investigative arm of Congress”.

The agency’s purpose is to improve government operations and save taxpayer money.

Instead, no one is held accountable for correcting the problems cited in the GAO reports.


An example is this 81-page report released last week:

Out of nine security violations, no actions to correct them have “been taken or are being planned.”

Who is in charge of the National Nuclear Security Administration?

Jill Hruby.

Read the full article at

New satellite images show Russia’s Poseidon nuke-carrying 600ft submarine Belgorod lurking in the Arctic amid fears Putin is planning to carry out a nuclear test

by Daily Mail


New satellite images show Russia’s huge nuclear submarine, allegedly carrying ‘apocalypse’ and ‘doomsday’ weapons, lurking around the Barents Sea as fears grow that Vladimir Putin is planning to carry out a nuclear test.

The nearly 600ft Belgorod submarine has disappeared from its home base in the Arctic Circle and may be on its way to the Kara Sea to test the Poseidon nuke, a NATO warning note leaked over the weekend has suggested.

Satellite images publihsed by Naval News show the submarine is currently operating on the surface in the Arctic.

The vessel was seen in the White Sea leaving Severodvinsk, a city in north Russia, a few weeks back. It was later spotted in the Barents Sea on September 22 and 27.

The Belogord, which is in the region of 30,000 tons, is the largest built submarine in the world since and armed with the Poseidon nuke.

Poseidon is a drone that is said to be capable of travelling huge distances underwater before detonating with enough force to trigger a 1,600ft nuclear tsunami designed to drown and irradiate coastal cities.

The US Navy has described the weapon as an ‘Intercontinental Nuclear-Powered Nuclear-Armed Autonomous Torpedo’ with ‘incredible range’ and ‘hard-to-kill performance.’

Read the full article at Daily Mail.

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