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Study: Science Used to Approve Antidepressant Drugs Does Not Show Efficacy

The largest, most expensive antidepressant efficacy study involving over 4,000 initial participants ended in 2006. The purported intention of the study was to provide real-life results instead of the shorter clinical trial results that are done to get antidepressant drugs approved. But the results were not clear regarding antidepressants' true efficacy compared to clinical trials. Safety was not a consideration, just efficacy at reducing depression. A new study has recently re-analyzed this massive STAR*D (Sequenced Treatment Alternatives to Relieve Depression) study funded by the National Institute of Mental Health (NIMH) and found evidence that there was obfuscation, intended or unintended, that made antidepressant efficacy look better than it actually is. Earlier this year, 2018, a published paper, Do outcomes of clinical trials resemble those “real world” patients? A reanalysis of the STAR*D antidepressant data, demystified this study and provided a clearer picture of real-world antidepressant efficacy. As one psychiatrist skeptical of antidepressants, Dr. Joanna Moncrieff, reported after reviewing the 2018 reanalysis of the STAR*D paper: "[The 2018 reanalysis was done] 14 years after the [STAR*D] study was finished. What in the world were the main findings of the world's largest ever antidepressant trial doing being presented now in a little-known journal? The answer may lie in the fact that they show how miserably poor the results of standard medical treatment for depression really are! … people taking antidepressants do not do very well. In fact, given that for the vast majority of people depression is a naturally remitting condition, it is difficult to believe that people treated with antidepressants do any better than people who are offered no treatment at all."

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Expert Warns of Antidepressants and Mental Health Screenings Linked to Violence

In the wake of recent senseless acts of violence, especially in schools, the mental health watchdog Citizens Commission on Human Rights International (CCHR) urged state authorities and educators not to adopt “mental health screening” in schools in the false hope that it could prevent the violence. Such screening could exacerbate the issue if it leads to children being prescribed psychotropic drugs, CCHR says. Independent of CCHR, Dr. David Healy, an international expert in psychopharmacology, estimated that 90 percent of school shootings, over more than a decade leading up to 2012, were linked to SSRI antidepressants (e.g., fluoxetine, paroxetine, sertraline, etc.). Dr. Healy further warned: “Violence and other potentially criminal behavior caused by prescription drugs are medicine’s best-kept secret.” In an international study released earlier this year, CCHR documented 36 school shootings and school-related acts of violence that date back to 1988. All of the crimes were committed by people either taking or withdrawing from psychiatric drugs. The end result was that 172 people were wounded and 80 were killed, according to the study.

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Antidepressants in Pregnancy Tied to Autism

A new study provides one more reason to think twice about these powerful drugs, especially if you are pregnant. After extensive reports showing the negative effects of antidepressants, this new study, which looked at nearly 150,000 babies, has found a link between antidepressants taken during pregnancy and autism in young children. Children of women who took antidepressants during the second and third trimesters of pregnancy were 87% more likely to develop autism than kids born to women who didn’t take the drugs.

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Study: Big Pharma’s Smoking Gun – Antidepressants Proven to Double Suicidality

Researchers from the University of Copenhagen, Faculty of Health and Medical Sciences, and Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark have conducted a systematic review and meta-analysis of the relationship between antidepressant treatment and increases in suicidality and aggression. Their study, published in the British Medical Journal, was based on 64,381 pages of clinical reports reveals new information on harms - pharmaceutical antidepressant treatment actually doubles the risk for suicidality in children and adolescents. "We believe ours is the first comprehensive review of randomised controlled trial data using clinical study reports for aggressive behavior and akathisia, and our finding of the doubling of aggression in children and adolescents is novel."

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New Evidence that Antidepressants Are Causing an Epidemic of Violence

An article in the current British Medical Journal explains why the link between antidepressants and the epidemic of violence is stronger than previously thought. ANH-USA has researched dozens of the most high-profile cases of violent crimes over the last few decades. We found that in just under half of the cases (eleven out of twenty-three), the perpetrator was documented to be taking, or had recently stopped taking, some form of antidepressant or antipsychotic medication. The FDA recognizes this, and many antidepressants carry “black box warnings,” the most stringent precaution a drug label can carry before being removed from the market. Many antidepressants carry a black box warning of an increased risk of suicidal thoughts and behavior. Dr. Robert Whitaker notes that there is also a shocking risk of increased violence to others, which is not highlighted in the black box.

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Antidepressants During Pregnancy Increase Risk of Autism

Researchers studied 966 mother-child pairs in order to examine the associations between prenatal use of serotonin reuptake inhibitors (SSRIs)—e.g., Prozac, Zoloft, Lexapro, Paxil, Celexa– and the odds of autism spectrum disorders and other developmental delays. The scientists found that among boys, prenatal SSRI exposure was nearly 3-fold higher in children with autism spectrum disorder relative to children with typical development. The authors concluded, “In boys, prenatal exposure to SSRIs may increase susceptibility to autism spectrum disorder or developmental delay.”

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Raising a Generation of Pill-Poppers: How Prescription Drug Abuse Threatens an Entire Generation

Far from being recognized for their potential health hazards, ADHD drugs have gained a reputation as “cognition enhancers” among students and young professionals. Narcotic painkillers, anti-anxiety drugs, and antidepressants are also notoriously overprescribed. Benzodiazepines, a class of anxiety drugs, are also widely overused, and a common source of drug addiction. Clearly, what we have here is a gigantic spinning merry-go-round of drug use and addiction to mind-altering medications, where one drug frequently leads to the use of another. The full societal ramifications of all this pain-avoidance, whether physical or emotional, and the insistence on immediate relief, are probably far greater than any of us can conceive.

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Mental illness: Is ‘Chemical Imbalance’ Theory a Myth? Answer: Yes

In the minds of many neuroscientists today, the chemical imbalance theory has turned out to be a myth, with little more scientific or medicinal substance than poetry or song. And the pills are now largely recognized by a multitude of experts, as well as some of the pharmaceutical companies that make them, as concoctions of magical thinking.

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Navy Yard Mass Murderer Aaron Alexis was Taking Antidepressant Trazodone – How Many More Drug Induced Shootings Until Lawmakers Wake Up?

Despite 22 international drug regulatory warnings on psychiatric drugs citing effects of mania, hostility, violence and even homicidal ideation, and dozens of high profile shootings/killings tied to psychiatric drug use, there has yet to be a federal investigation on the link between psychiatric drugs and acts of senseless violence. How many mass shootings have to occur by shooters with a psychiatric drug history before those who have the power to make a difference finally take the necessary action to protect the American people? The list of shooters receiving psychiatric care and psychiatric drug use is long. In just a little over a year there have been three such mass shootings, including Aurora, Co., Newtown, Ct., and now the Washington Navy Yard, totaling 52 dead and 69 injured. In each case, as in dozens of other mass shootings, the common denominator is that the shooters were either receiving psychiatric care, taking mind altering psychiatric drugs or both.

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Medicaid is Drowning Our Kids in Toxic Psychiatric Drugs

The number of children on Medicaid taking antipsychotic drugs has tripled in just ten years—and shockingly, many of them are under the age of three. Note that these are not just antidepressants, which are bad enough. We are talking about strong antipsychotic drugs. These are so strong that many adults stop taking them because of severe side effects. How can a three-year-old protect himself or herself from the toxic effects of these drugs on their undeveloped brains and bodies?

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FDA Approves a Dangerous New Antidepressant—for Hot Flashes!

The FDA has approved the first non-hormonal treatment for hot flashes associated with menopause. The drug is paroxetine mesylate (marketed as Brisdelle). Paroxetine, an SSRI, is the active ingredient in two drugs for depression and other psychiatric disorders, Paxil and Pexeva. What is not mentioned is that the FDA’s Reproductive Health Drugs Advisory Committee voted 10 to 4 that the overall risk-benefit profile of the drug did not support approval—that the benefits over placebo were “minimal,” and that all of the severe side effects associated with SSRIs, such as suicidal thoughts and osteoporosis, outweigh the minor benefits.

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Science Confirms Turmeric As Effective As 14 Drugs

Turmeric is one the most thoroughly researched plants in existence today. Its medicinal properties and components (primarily curcumin) have been the subject of over 5600 peer-reviewed and published biomedical studies. In fact, our five-year long research project on this sacred plant has revealed over 600 potential preventive and therapeutic applications, as well as 175 distinct beneficial physiological effects. Given the sheer density of research performed on this remarkable spice, it is no wonder that a growing number of studies have concluded that it compares favorably to a variety of conventional medications.

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Steve Forbes Uninformed About Antipsychotic Drugs Link to Violence and Suicide

by Alliance for Natural Health

Will that avoid mass shootings like Sandy Hook—or just put people on the very drugs that can make them homicidal?

In the January 21 issue of Forbes magazine, Steve Forbes says that hundreds of thousands of people lead tortured, miserable lives and need supervised care. His solution is to repopulate public mental hospitals and wards instead of […]

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Anti-depressants Can Cause Sudden Death

Most antidepressants cause a change in the electrical pulse of the heart, which changes the rhythm of the heart beat. It’s called an extended QT interval—and it can result in sudden death with no warning of any kind: BMJ study.

by Heidi Stevenson
Gaia Health

The antidepressant citalopram—brand names Celexa and Cipramil—has joined a growing list of […]

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Pharmacists Want to Classify Herb as a Drug to Protect Anti-depressant Drugs

by Alliance for Natural Health
A Natural, Inexpensive, Easily Accessible, Safer Treatment for Depression?
Not if pharmacists have their way! Action Alert!

Pharmacists Planning Service (PPS), a “public health, consumer, and pharmacy education” nonprofit, is petitioning the FDA to change the designation of St. John’s Wort from “herbal dietary supplement status” to “behind pharmacy counter status” (BPCS)—a designation that requires pharmacist […]

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Random Violence & Senseless Shootings: Police data may I.D. psychiatric drug use in violent crimes

By Kelly Patricia O’Meara
The Citizens Commission on Human Rights

Law enforcement is in a unique position to collect data that may actually provide the most accurate information about the possible connection between psychotropic  drugs and violence.

Image caption: 22 international drug regulatory warnings cite psychiatric drugs causing violent reactions including mania, psychosis, hostility, violence and homicide.

In an effort […]

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Government Addresses Suicides Without Looking at Suicide-Linked Drugs

 

by Martha Rosenberg
CounterPunch.com 

Excerpts:

It would be laughable if it weren’t tragic. This week Surgeon General Regina Benjamin introduced a plan to stem the nation’s growing suicide rate without addressing the nation’s growing use of suicide-linked drugs.

Antidepressants like Prozac and Paxil, antipsychotics like Seroquel and Zyprexa and anti-seizure drugs like Lyrica and Neurontin are all linked […]

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