October 22, 2014

Gardasil Vaccine Claim for Preventing Cervical Cancer Not Backed by Science

Pin It

Health Impact News Editor Comments: This article is from Discover Magazine, which is generally a pro-vaccine publication, and the author is a medical investigative journalist for the British medical journal (BMJ), who is not anti-vaccine. So it is not simply the anti-vaccine crowd that is complaining about the lack of science behind the Gardasil vaccine, which is linked to very serious side effects, including death. If Gardasil does not even do what it is marketed to do, then all arguments concerning its safety and who should be getting it become irrelevant. With the FDA removing the approval of the breast cancer drug Avastin this week, and remembering the removal of another Merck product a few years ago, the drug Vioxx, which reportedly led to tens of thousands of deaths before it was removed from the market, one has to wonder if it is only a matter of time before Gardasil is also removed from the market after closer scrutiny and more adverse reactions?  See also the earlier report concerning women in Australia are suing Merck over Gardasil adverse reactions, something Americans cannot do because of legal immunity for vaccine makers. This legal protection for U.S. vaccine makers which prevents you from suing them if they make a product that injures you or causes death, was upheld by the U.S. Supreme Court earlier this year.

Should Boys Be Given the HPV Vaccine? The Science Is Weaker than the Marketing

by Jeanne Lenzer
Discover Magazine

Merck’s promotion of Gardasil, its vaccine against the human papilloma virus (HPV), has a complicated history. First there was the exuberant claim about its reputedly great effectiveness in preventing cervical cancer. Now comes the recommendation last month from the Centers for Disease Control and Prevention, that all 11- and 12-year-old boys should be given the vaccine.

Of Science and Truthiness

The vaccine for boys is important, say advocates, because reducing HPV in boys will reduce transmission to girls and women—only 32 percent of whom have been getting the shots to date. Giving the shots to boys, they say, promotes gender equity. As a bonus, the vaccine may protect against oral and anal cancers in men who have sex with men.

Since a key part of the rationale for vaccinating boys is to protect girls, it’s worth a moment to examine the claims about reducing cervical cancer deaths. Merck won approval for Gardasil from the Food and Drug Administration in June 2006. On May 10, 2007, Merck published the results of a study in the New England Journal of Medicine that claimed an astounding 98 percent efficacy in preventing changes in the cervix used as a marker for cervical cancer.

But that statistic begs closer examination.

To achieve the 98 percent efficacy claim, Merck excluded from analysis anyone who “violated” the study protocol. In other words, all real-world problems that arose were excluded from analysis. Problems like girls who refused to take a second or third shot after they became sick and (correctly or incorrectly) blamed the vaccine. Or doctors who incorrectly gave the vaccine to someone who shouldn’t have received it. While it’s worth knowing how effective the vaccine is when it’s used exactly as it should be, for a public-health decision, it’s not as relevant as its real-world effectiveness.

To Merck’s credit, they reported that when all women in the study were analyzed, the vaccine’s efficacy dropped to 44 percent. Still, 44 percent might be considered a smashing success when you’re talking about saving lives. Except for one thing: the numbers get worse. The 44 percent benefit included only those women with the two specific cancer-causing HPV strains found in the vaccine. But when the researchers looked at negative cervical changes from any causes, they found that changes occurred in unvaccinated women at a rate of 1.5 events per 100 person-years, while vaccinated women had 1.3 events—dropping the benefit to 17 percent.

Moreover, most of the cervical changes tracked by the researchers weren’t even indicative of cervical cancer in the first place. Most were innocent cellular abnormalities that either disappear entirely on their own, or never progress to cancer. In fact, when they looked more closely at advanced cervical changes most likely to progress to cancer versus more innocent changes that go away spontaneously, it was the innocent changes that accounted for the decline.

Whether Gardasil will reduce cervical cancer deaths in real-world conditions has simply never been answered. It might—but that would take a long-term study, and one that should be done before it’s widely promoted.

A Cure in Need of a Disease

Now, come the boys. If cervical cancer prevention and gender equity don’t have you jumping out of your seat to grab every preteen boy to get a shot, what about the claim that Gardasil might prevent anal and oral cancers men may get from having sex with other men?

Merck says that in males, the vaccine is 89 percent effective against genital warts and 75 percent effective against anal cancer. On closer inspection, some of the numbers don’t just deflate, they evaporate. First off, let’s define the problem: The annual number of deaths from anal-rectal cancer among all men in the U.S. is 300. And how did Merck get its happy statistics on efficacy? Once again, they reported an idealized benefit by excluding from analysis 1,250 study violators out of 4,055 total test subjects. When the real-world analysis was conducted, the numbers plunged—right down to plum nothing. After evaluating tissue changes in male genitalia that were suggestive of a cancer precursor, Merck reported that vaccine efficacy against such lesions “was not observed.”

Given this, is it worth the risk of exposing millions of youth to the as yet uncertain harms of the vaccine? The CDC states that in rare instances, some vaccines may trigger the potentially fatal and paralyzing condition Guillain-Barré, and Nizar Souayah, MD, of the University of Medicine and Dentistry of New Jersey in Newark, says he and his colleagues found “clear evidence from our database of an increased incidence of Guillain-Barré syndrome in the first six weeks, especially the first two weeks, after [HPV] vaccination.” Guillain-Barré is very rare, even among people who are HPV vaccinated, but the problem is emblematic of the downsides of subjecting millions of people to any medical treatment.

Mo’ Money, Mo’ Money, Mo’ Money

So how did the HPV vaccine become a multi-billion-dollar winner for Merck? Well you might not be surprised to hear that the company happily lavished money on doctors, professional societies, and over 100 legislators. Of course, there is no tie between the recipients of this largesse and their promotion of the vaccine, say beneficiaries like presidential candidate and current Texas governor Rick Perry. In 2007, Perry signed an executive decree mandating that all girls in Texas receive the vaccine. The $28,500 Perry received was minor compared to his other connection to Merck: Perry’s chief of staff, Mike Toomey, became a lobbyist for Merck, championing the HPV vaccine. Once in that position, announced his plans to raise over $50 million for Perry’s presidential campaign.

In any case, the marketing certainly doesn’t seem to have hurt the adoption of Gardasil, which has been administered to millions of girls around the country. Caught up in the joy, some 41 state legislatures have initiated bills to promote or mandate the shots for all girls. With the CDC’s new recommendation for boys, one can imagine that promotion or mandates for them might come next.

Fortunately, some researchers don’t believe the hype. Dr. Diane Harper, one of the lead researchers in the development of the HPV vaccine, recently told the Kansas City Star, the vaccine for boys is “pie in the sky…We’re short of health care dollars. Why should we spend it on that?”

Indeed. There are better ways to spend the billions of dollars currently being spent on HPV vaccines. First, we already have a pretty terrific way to prevent most cervical cancer deaths, and it’s called the Pap smear. Since poor women are less likely to get Pap smears and more likely to die from cervical cancer, we could start by extending medical services to them. Second, many oral cancers are caused by smoking, and men and women who smoke are more likely to die of oral and cervical cancer, so we could invest in smoking cessation efforts.

As Angela Raffle, a specialist in cervical cancer screening, told the New York Times‘ Elisabeth Rosenthal, “Oh, dear. If we give it to boys, then all pretense of scientific worth and cost analysis goes out the window.”

Unfortunately, the hope that we would undertake low-tech, high-yield public health efforts might be the real pie in the sky thinking.

Full disclosure: I am not anti-vaccine. I’m happy to sport that little scar on my thigh from the smallpox vaccine I received as a kid. Smallpox is a scourge I can live without. Nor do I believe that every claim of calamity occurring after a vaccine is due to the vaccine. What I question is the promotion of vaccines, drugs and medical devices that aren’t backed up by solid clinical evidence and shown to be cost-effective in the real world.

Read the Full Article Here: http://blogs.discovermagazine.com/crux/2011/11/14/should-boys-be-given-the-hpv-vaccine-the-science-is-weaker-than-the-marketing/

 

pin it button Gardasil Vaccine Claim for Preventing Cervical Cancer Not Backed by Science

We Lost the War on Cancer – Review of Alternative Cancer Therapies

we lost the war on cancer Gardasil Vaccine Claim for Preventing Cervical Cancer Not Backed by Science

We have lost the war on cancer. At the beginning of the last century, one person in twenty would get cancer. In the 1940s it was one out of every sixteen people. In the 1970s it was one person out of ten. Today one person out of three gets cancer in the course of their life.

The cancer industry is probably the most prosperous business in the United States. In 2014, there will be an estimated 1,665,540 new cancer cases diagnosed and 585,720 cancer deaths in the US. $6 billion of tax-payer funds are cycled through various federal agencies for cancer research, such as the National Cancer Institute (NCI). The NCI states that the medical costs of cancer care are $125 billion, with a projected 39 percent increase to $173 billion by 2020.

The simple fact is that the cancer industry employs too many people and produces too much income to allow a cure to be found. All of the current research on cancer drugs is based on the premise that the cancer market will grow, not shrink.

John Thomas explains to us why the current cancer industry prospers while treating cancer, but cannot afford to cure it in Part I. In Part II, he surveys the various alternative cancer therapies that have been proven effective, but that are not approved by the FDA.

 

Read We Lost the War on Cancer – Review of Alternative Cancer Therapies on your mobile device!

FREE! – $0.99

appstore icon Gardasil Vaccine Claim for Preventing Cervical Cancer Not Backed by Science

googleplay app store Gardasil Vaccine Claim for Preventing Cervical Cancer Not Backed by Science

kindle logo sm Gardasil Vaccine Claim for Preventing Cervical Cancer Not Backed by Science

nook logo Gardasil Vaccine Claim for Preventing Cervical Cancer Not Backed by Science

 


Know your rights and the exemptions available!
Free Shipping Available

0 commentsback to post

Other articlesgo to homepage

Prescription Drugs Now Factor in Higher Percentage of Fatal Car Crashes Than Alcohol or Marijuana

Prescription Drugs Now Factor in Higher Percentage of Fatal Car Crashes Than Alcohol or Marijuana

Pin It

Prescription drugs and multiple drug combinations are frequently found in the blood of drivers involved in fatal car crashes on US roads, according to a new study in Public Health Reports. Drivers today are more likely to test positive for drugs than drivers 20 years ago, and drugged drivers are now likely to be older than 50. Gone are the days when drunk drivers were our only concern—alcohol is but one of MANY drugs that can make you dangerous behind the wheel. And now many people are on multiple drug cocktails, especially prescription drugs, which multiplies their impairment.

Use of Aborted Human Cell Lines in Vaccines Linked to Rise in Autism

Use of Aborted Human Cell Lines in Vaccines Linked to Rise in Autism

Pin It

Researchers from the Sound Choice Pharmaceutical Institute recently published a study showing a correlation with the introduction of human fetal cell lines used as contaminants in childhood vaccines, and the rapid rise of autism. The study was published in the Journal of Public Health and Epidemiology, an open access Academic Journal.

I reviewed the full length research paper and found the methodology of the research very thorough. The researchers tracked not only the introduction of aborted fetal cell lines introduced into vaccines used in the childhood vaccination scheduled in the United States, but they also tracked standards for autism diagnoses as published in the Diagnostic and Statistical Manual. This manual is used in the field of psychology and has undergone several revisions. One of the claims made for the rising rate of autism in America today is that it is primarily related to changes of diagnosis. This study used sophisticated software to account for these changes in autism diagnosis, and found:

“Autistic disorder change points years are coincident with introduction of vaccines manufactured using human fetal cell lines, containing fetal and retroviral contaminants, into childhood vaccine regimens. This pattern was repeated in the US, UK, Western Australia and Denmark. Thus, rising autistic disorder prevalence is directly related to vaccines manufactured utilizing human fetal cells. Increased paternal age and DSM revisions were not related to rising autistic disorder prevalence.”

Boston Nurses Speak Out Against Mandatory Flu Shots

Boston Nurses Speak Out Against Mandatory Flu Shots

Pin It

Last month (September 2014) the Massachusetts Nurses Association sued Brigham and Women’s Hospital over a new policy that required nurses to receive the annual flu vaccine as a condition for employment.

The nurses were, of course, criticized by the medical establishment. They were accused of putting their own interests above the needs of patients. Lynn Nicholas, president of the Massachusetts Hospital Association, stated that the nurses were: “putting a pet peeve of theirs above the safety and well-being of the patients they serve, their families, visitors to the hospital, and their colleagues.”

Pet peeve? Really?

When nurses all across the United States and Canada are willing to sacrifice their jobs and careers to avoid the annual flu shot, it is time to sit up and take notice. This is obviously something much more than a “pet peeve.”

Trish Powers, representing Brigham nurses in Boston fired back a comment that The Boston Globe published. It is titled “Brigham nurses know flu vaccine can do harm.”

Gardasil: The Day Our Daughter’s Life Changed

Gardasil: The Day Our Daughter’s Life Changed

Pin It

The Gardasil vaccine has changed Skylee’s life in so many ways and we do not know how many more symptoms will show up and change her life even more than it has already done. Our whole family has been affected by this vaccine and all of our lives have been turned upside down that terrible day in 2013.

If only the doctors would recognize Skylee has gone from being a healthy young girl to an invalid when the only major change in her life occurred on the day she had that single shot of Gardasil.

Will There Be An Ebola Outbreak in America?

Will There Be An Ebola Outbreak in America?

Pin It

So here is what inquiring minds want to know:

Why did U.S. health officials in Atlanta and on the ground in Africa ignore the exploding Ebola epidemic last spring?

Why did U.S. government officials fly American aid workers infected with Ebola to the U.S. rather than treating them with experimental drugs at hospitals in Africa?

Why did the U.S. government press the United Nations to adopt a resolution calling for no restrictions on international travel from Liberia and other Ebola-stricken countries?

Why did the Centers for Disease Control, supposedly the world’s leading infection control agency, fail to immediately assist Texas health officials when the first case of Ebola was diagnosed on US soil to guarantee that, at a minimum, the kind of infection control measures used in most nursing homes in America would be carried out?

Why has the Director of the CDC repeatedly stated that the only way a person can transmit Ebola is if they have a fever and said that people cannot get Ebola unless they have direct contact with the body fluids of an infected person – but that under no circumstances is Ebola airborne – when he knows, or should know, those statements could be false?

And why are experimental Ebola vaccines being fast tracked into human trials and promoted as the final solution rather than ramping up testing and production of the experimental ZMapp drug that has already saved the lives of several Ebola infected Americans?

A logical conclusion is that some people in industry, government and the World Health Organization did not want the Ebola outbreak to be confined to several nations in Africa because that would fail to create a lucrative global market for mandated use of fast tracked Ebola vaccines by every one of the seven billion human beings living on this planet.

read more


Get the news right in your inbox!