August 20, 2014

Capric Acid from Coconut Oil May Lead to Better, Safer Drug for Diabetes

pin it button Capric Acid from Coconut Oil May Lead to Better, Safer Drug for Diabetes

health benefits of coconut oil 300x140 Capric Acid from Coconut Oil May Lead to Better, Safer Drug for Diabetes

Health Impact News Editor Comments: Since coconuts are a food and cannot be patented, many will continue to look for ways to “improve” upon nature and find components of the coconut, particularly the oil, that can be made into some kind of drug form that can be patented. This study deals with one of the fatty acid chains found in coconut oil, Capric Acid. Studies for a number of years now have shown that the medium chain fatty acids found in coconut oil are particularly helpful for diabetes (See 2009 study and this 2010 study.) In fact, replacing refined carbohydrates in one’s diet with saturated fats can drastically help diabetes (see this study as an example). So even though this specific study is identifying one specific fatty acid chain in coconut oil that is helpful for diabetes, why not just stick with the whole food of coconut oil? Just maybe the coconut was created by a master designer to work in harmony with all of the fatty acids that make up coconut oil!

by the Van Andel Research Institute

Van Andel Institute study may lead to better, safer drug for diabetes

Study reveals a natural fatty acid used in manufacturing can modulate glucose control

Grand Rapids, Mich. (November 21, 2011) A Van Andel Research Institute (VARI) study published recently in the Journal of Biological Chemistry reveals that a natural fatty acid can serve as a regulator of blood sugar levels, which may have important applications in designing better and safer drugs for diabetes treatment.

According to the U.S. Center for Disease Control and Prevention (CDC), nearly 26 million Americans have diabetes, and current drugs commonly used to treat the disease sometimes have unwanted side effects.

The study found that decanoic acid, a saturated fatty acid, acts as a modulator of a sub-family of nuclear receptors (peroxisome proliferator-activated or PPAR receptors) that play a key role in glucose and lipid metabolism.

Decanoic acid, also known as “Capric acid,” occurs naturally in coconut oil and palm kernel oil, as well as in the milk and animal fats of some mammals. It is used in organic synthesis and is common in the manufacture of perfumes, lubricants, greases, rubber, dyes, plastics, food additives and pharmaceuticals.

“We studied a nuclear receptor (PPARγ) that plays a key role in glucose and lipid metabolism and is the molecular target of the thiazolidinedione (TZD) class of antidiabetic drugs, which have been shown to have negative side effects such as weight gain, fluid retention, and increased risk for cardiovascular diseases,” said H. Eric Xu, Ph.D., Director of VARI’s Center for Structural Biology and Drug Discovery. “Our results showed that decanoic acid could be used in designing better and safer PPARγ – based drugs.”

Xu’s laboratory uses a technique known as X-ray crystallography to determine exactly how and why the drug compounds work in molecular detail, which can then help drug developers engineer more potent drugs that have fewer unwanted side effects. The lab has previously published studies that could impact a variety of diseases, including osteoporosis, diabetes, and anxiety and depression disorders.

The recent study, which was carried out in collaboration with a team of international research and clinical partners from Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, National University of Singapore, The Scripps Research Institute, Shanghai Institute of Materia Medica, and University of Michigan showed that decanoic acid is a direct ligand, or binding partner, of PPARγ, and binds and partially activates PPARγ without leading to the development of fat cells.

“Treatments with decanoic acid and its triglyceride form improve glucose sensitivity and lipid profiles without weight gain in diabetic models,” said lead author Venkata R. Malapaka, Ph.D., who conducted his research at Van Andel Research Institute and now works as a Research Fellow in Brigham and Women’s Hospital’s Center for Interdisciplinary Cardiovascular Sciences. “Together, these results suggest that decanoic acid is a modulating ligand for PPARs and the structure can aid in designing better and safer PPARγ-based drugs.”

In additional to the nearly 26 million Americans with diabetes, an estimated 79 million U.S. adults have prediabetes, a condition in which blood sugar levels are higher than normal, but not high enough to be diagnosed as diabetes. Prediabetes raises a person’s risk of type 2 diabetes, heart disease and stroke. Diabetes affects 8.3 percent of Americans of all ages, and 11.3 percent of adults aged 20 and older. About 27 percent of those with diabetes—7 million Americans—do not know they have the disease. Prediabetes affects 35 percent of adults aged 20 and older.

Read the full press release here: http://www.eurekalert.org/pub_releases/2011-11/vari-vai112111.php

 

Virgin Coconut Oil:
How it has changed people’s lives and how it can change yours!

BVCNOcover Capric Acid from Coconut Oil May Lead to Better, Safer Drug for Diabetes

Includes 85 recipes – Free shipping available!

freecoconutrecipes Capric Acid from Coconut Oil May Lead to Better, Safer Drug for Diabetes

0 commentsback to post

Other articlesgo to homepage

Users Testify to Coconut Oil “Miracles” on WebMD

Users Testify to Coconut Oil “Miracles” on WebMD

Pin It

WebMD is the world’s most visited “health” website. They derive their advertising from the pharmaceutical industry, so they have a pro-Pharma slant, as one can expect. It is not typically the place you would go to find information regarding alternative treatments to FDA approved pharmaceutical drugs. If you are contemplating using prescription drugs, it is a great place to get information about the medical industry’s products. If however you are looking for information on products that are not approved as drugs by the FDA, their information will be highly biased.

Due to the increasing popularity of coconut oil and its healing properties, WebMD now has a listing for coconut oil. It is listed in their vitamin and supplement section, since it is not approved as a drug, and since they generally do not provide any health information about foods.

They give the standard pro-Pharma view of coconut oil, which is that, in their view, there are no approved claims for coconut oil. They also warn people that coconut oil could raise cholesterol levels and could be harmful, even while acknowledging that research actually shows the opposite, since coconut oil traditionally lowers LDL cholesterol while raising HDL cholesterol (a positive thing.) They also warn that if people eat too much coconut oil, since it is fat, that it could lead to weight gain.

Interestingly, WebMD allows users to comment on these entries, presumably in a format where patients can comment on their own experiences with the vast array of drugs listed on their website. Read what users said about the “miraculous” properties of coconut oil in relation to Alzheimer’s, Parkinson’s, weight control, memory, mood swings, energy, dry skin, dental health, stopping seizures and more.

Adding Coconut Oil into Your Fitness Routine

Adding Coconut Oil into Your Fitness Routine

Pin It

Fitness junkies, take note: you need coconut oil. Coconut oil straight up, in your protein-rich meals, protein shakes, snacks, pre-workout, post-workout fuel – whatever you choose. Coconut oil can be adapted into your style of eating and seriously enhance the results of the style of fitness you’re into, be it body building, toning, endurance, or general weight and muscle management.

So why add coconut oil into your fitness routine? Coconut oil is a rich source of MCTs (medium chain triglycerides), a high-energy fuel that the body uses to prevent muscle loss, but take off body fat. Coconut oil has a lot of these MCTs. Eat it.

Easy Homemade Coconut Oil Chocolate Recipes

Easy Homemade Coconut Oil Chocolate Recipes

Pin It

Coconut oil makes fantastic homemade chocolate. With just a few extra ingredients, coconut oil will morph into an impressively smooth, rich dark chocolate that won’t require a chocolate-making class to learn.

The easiest coconut oil chocolates require no cooking and generally all the ingredients are blended together in one easy step.

How to Use Coconut Oil in Your Skincare Routine

How to Use Coconut Oil in Your Skincare Routine

Pin It

Coconut oil is often praised for its many health benefits and its versatility in cooking and baking. While these many benefits may have gotten you to commit to always keeping some coconut oil in your pantry, coconut oil has a big place outside of the kitchen as well.

Coconut oil’s healing, antibacterial, and cleansing properties take on an entirely new personality when used topically, making it the ideal multiple-products-in-one item to add to your skincare and personal grooming regimes. Since coconut oil is gentle on the skin and not laden with chemicals and ingredients you have to watch out for (like most of the skin and beauty care products sold today), this is a safe and easy oil for anyone to use and experiment with.

Here are 4 popular ways coconut oil can be used to replace the dozens of pricey, and often ineffective, products sitting in your bathroom.

10 Different Ways to Eat Coconut Cream Concentrate

10 Different Ways to Eat Coconut Cream Concentrate

Pin It

Coconut Cream Concentrate, also known as “coconut butter” is a nut butter-like spread made from coconut.

Coconut Cream Concentrate definitely should have a place in every coconut lover’s pantry. Since it is 100% coconut, it also has a substantial amount of coconut oil, making it perfect for those who are looking for more creative ways to get coconut oil into their diets.

How many different ways can you use it? Aside from enjoying it by the spoonful or eating it on pastries, here are just 10 of the countless, creative ways you can use this delicious coconut butter.

read more


Get the news right in your inbox!