Since 2015 there have been a few pharmaceutical companies working on a new cholesterol-lowering drug type as a replacement for the older class of statin drugs, such as Lipitor. Lipitor was the best-selling drug of all time, but its patent expired a few years ago. The new mantra is getting LDL cholesterol levels lower than statin drugs. The drug class of these new cholesterol-lowering drugs is a PCSK9 inhibitor. Of course, this is madness for two reasons: (1) Cholesterol and fats, in general, are not the cause of heart disease; (2) cholesterol is vital for hormone production and nervous system and brain function. The fact is that cholesterol is vitally essential for good health, and lowering cholesterol artificially can and does lead to more immediate health problems, and a lower life expectancy. So why the focus for a new cholesterol-lowering drug? Once again, we follow the money.
Statin drugs that reduce cholesterol in the body are much more harmful than beneficial, even though they do lower cholesterol readings. There is much clinical evidence that lowering cholesterol is not only unnecessary, but it is seriously damaging to overall health. This is worth repeating even as much as Health Impact News has covered cholesterol and statin issues in the past. Many others, even alternative health sites and practitioners, still continue to perpetuate the cholesterol myth that promotes the scam of dangerous and highly profitable statin drugs. Epidemiological studies tracking elderly people over time have concluded that people with high cholesterol live longer than those with low cholesterol. So there is no need to take a pharmaceutical with dangerous side effects to lower cholesterol.
The best metric for measuring the effectiveness of a drug is the NNT or the number of patients needed to be treated with the drug to prevent 1 clinically significant endpoint. In the case of statins and presumably in the case of the new class of drug to lower cholesterol the NNT for primary prevention is between 100-500!! I would not want to take an expensive dangerous drug that is likely to increase my incidence of diabetes (which in and of itself increased heart attacks), heart failure, dementia, muscle aches, fatigue, and oxidative stress as a result of lower vitamin D and coenzyme Q10. For what? To lower my chances of an MI or stroke by less than 1%? I would rather take up jogging and eat better. I would rather bet on black. The statin drugs have been a disaster as they don’t work in the majority of people who take them. Now, we want to spend over $14,000 per year in a new class of cholesterol-lowering drugs? We must be out of our minds.
A recent study in Critical Care Medicine is titled, “Lipid Paradox in Acute Myocardial Infarction- The Association with 30-Day In-Hospital Mortality.” This study followed 724 hospitalized patients who suffered an acute heart attack (i.e., myocardial infarction). The scientists attempted to clarify the relationship between the lipid profiles and the 30-day mortality in patients who suffered a heart attack. The authors found that those with lower LDL-cholesterol and triglyceride levels had a significantly elevated mortality risk when compared to patients with higher LDL-cholesterol and triglyceride levels. Why would lowered cholesterol and triglyceride levels be associated with a higher mortality rate? Fats from triglycerides are a major energy source and LDL-cholesterol is critical for cell membrane synthesis and is needed to fight infections. Adequate LDL-cholesterol and triglyceride levels may be critical for cell function and survival in the case of a heart attack—as well as in other conditions. Folks, we have been hoodwinked to believe that we must all take cholesterol-lowering medications in order to prevent and/or treat heart disease. People do not get heart disease because their cholesterol level is elevated. Remember, 50% of patients who suffer a heart attack have normal cholesterol levels.
Shocking news! Two studies were recently published that endorse 2013 guidelines for a wider use of statin drugs. As reported in the Journal of the American Medical Association (JAMA), out of over 2400 people, 39% were statin eligible, compared with 14% by the old 2004 guidelines. In one fell swoop, the amount of people recommended for statin use was tripled! This is not surprising given the amount of revenue from statin drug sales. Who makes the guidelines? Doctors on Big Pharma payroll, that’s who.
My father was a cardiologist who started his practice in the 1970’s. In those days, the beauty and art of medicine were in the diagnosis of heart disease. They didn’t have many “tools” to treat patients. There were only a few pharmaceuticals and surgery was new on the scene. Fast forward to 2015. If you walk into a cardiology office you will walk out with a stack of prescriptions and orders for testing such as treadmills and ultrasounds. But what are the benefits?
As reported in the New York Times (2.20.15), a nutrition advisory panel that shapes U.S dietary advice eased some of the previous restrictions on fat and cholesterol, while at the same time recommending Americans lower their consumption of sugar. For many years, I have been writing and lecturing about the idiotic cholesterol and fat guidelines that the Powers-That-Be have been espousing. Over 30 years ago, we were told to eat less fat and cholesterol in order to lower our risk from dying from cardiovascular disease. During that same time we were encouraged to increase our consumption of carbohydrates in the form of grains and bakery products. We followed the Powers-That-Be’s advice and guess what? Our health has worsened. During the time we lowered our fat and cholesterol intake, we suffered with more obesity, diabetes, and heart disease.
The cholesterol-lowering statin drug empire continues to crumble. On Sunday February 15, 2015, the Sunday Express in the UK published a headline story stating that Oxford professor Dr. Rory Collins, whose research had been used to support putting millions of patients on statin drugs, was reassessing the data behind those studies for possible drug side effects. According to the Express: "Although the original research looked at the effect of statins on the heart and considered cancer risks it did not examine other side effects." This announcement by Dr. Collins is stunning, to say the least, and points to a massive cover-up and scandal related to statin drugs.
Statins work by poisoning an enzyme (HMG-CoA reductase) which is needed to produce cholesterol, adrenal and sex hormones, memory proteins and maintain cell energy. The highest concentration of cholesterol in the body is found in the brain. There were 36,605 reports of brain dysfunction from the FDA Adverse Events Databases which included memory impairment, transient cases of global amnesia, confusion, paranoia, disorientation, depression, and dementia related to statin use. Remember, this number is thought to represent only 1-10% of the true number of adverse drug reactions.
The $100 billion dollar cholesterol-lowering statin drug industry is under attack, as thousands of Americans are filing lawsuits against the manufacturers cholesterol-lowering drugs such as Lipitor. Research continues to confirm just how dangerous these drugs are, with yet another study published recently linking increased statin drug use to type 2 diabetes. One in four Americans over the age of 45 are currently on statin drugs. In spite of the increased research linking these drugs to diabetes, Alzheimer's Disease, liver damage, breast cancer, among many others, government-funded Big Pharma agencies continue to promote statin drugs and are attempting to get more Americans to take them. New guidelines put out by the American Heart Association earlier this year (2014) would more than double the number of Americans taking statin drugs. If we follow the pattern of Big Pharma when their products can no longer be supported in a free market due to lack of consumer confidence and demand, and massive litigation due to faulty products, they will probably seek some kind of government protection from these lawsuits. Such government protection will allow them to distribute their cholesterol drugs through government drug programs such as Medicare and Medicaid, and the new Obamacare. With the baby boomer generation heading into their senior years, it is just too large of a market for them to give up without a fight. The logic they will use with politicians in Washington D.C. will be very similar to the logic currently used by the vaccine market: Americans are too stupid to know better, so we need laws to protect us and our products against litigation so we can continue to manufacture and distribute them to people who don't want them, because they don't realize how much they need our drugs. We are currently living in the Dark Ages when it comes to health freedom, as today's pharmaceutical companies are the biggest criminals in the marketplace, having reached settlements in criminal medical abuses that reach into the billions of dollars. Yet the government continues to not only recommend their products, but purchase and distribute them with YOUR tax dollars via government funded programs such as Medicare, Medicaid, and Obamacare. As a consumer, you must resist purchasing these toxic products, and fight against any kind of mandated "health program" that forces you to purchase or take their products. History will look back on these Dark Days of medical tyranny with horror. In the meantime, don't become a fatality and statistic to the cholesterol drug scam! If you are responsible for caring for any seniors, help them to not become a fatality or statistic as well, by being informed and taking a stand for your rights!